Anime Crossover Defense Artifacts – All effects and how to get them

Learn all about the best and worst Artifacts for your favourite Anime Crossover Defense units here

Anime Crossover Defense Artifacts – All effects and how to get them

Anime Crossover Defense Artifacts offer a simple path to potentially game-changing unit upgrades.

If you’ve hit a wall with your current units and can’t afford to pull and upgrade more, farming for the best artifacts in Anime Crossover Defense could be the answer. Unlock them, equip them, and you’re off.


All Anime Crossover Defense Artifacts

Here’s every Artifact in Anime Crossover Defense, their skills, effects, and secondary unlocks at level 5:

  • Eternal Eye
    • Genjutsu – Causes the target to walk the wrong way.
    • Black Flames – Apply black flames to the target.
  • Dragon Radar
    • Dragon Sphere Search – A Dragon Sphere drops after every 2nd wave. Collect 7 to make a wish for Money, Power, or Enemy Rewind.
  • Black Notebook
    • Fate Written – The unit immediately defeats targets struck below a certain HP percentage.
  • Strand of a Hero’s Hair
    • One for All! – The unit executes a powerful attack and pushes targets back.
  • Hat of the CEO
    • Opportunist – Slightly increases the coins the unit earns.
  • Philosopher’s Stone
    • Equivalent Exchange – The unit’s damage increases each time it defeats a target.
  • Nimbus
    • Cloud Transportation – Hugely reduces the unit’s placement cost but increases its cost.
  • Uta Uta
    • Joyous Song – Improves the unit’s buffs and buffs others around it.
  • Key of Kings
    • King’s Vault – Reduces the unit’s placement cost.
    • King’s Treasure – Reduces the unit’s upgrade cost.
  • Divine Eye
    • Superior Dojutsu – The unit gains small stat boosts and can no longer be stunned.
    • Elemental Mastery – The unit’s attacks will always be of the strongest element against its target.
  • Hollow Mask
    • Hollow Mask – Massively increases unit’s damage for a short while.
  • Cursed Finger
    • Everlasing Curse – Increases damage over time durations.
    • King of Curses – Increases damage over time damage.
  • Hogyoku
    • Metamorphosis – Unit gains a massive Damage boost after clearing a large number of waves.
    • Desire Materialization – Slightly increases unit’s damage and reduces its upgrade costs.
  • Vampire Mask
    • Vampire Lord – Summons a zombie periodically
    • Haemorrhage – Bleeds the target dealing damage over time (can stack with other Bleed)

Anime Crossover Defense Artifacts tier list – Best artifacts for each unit

We’ll update soon with an Anime Crossover Defense tier list outlining the best artifacts for each unit.

How to get Artifacts in Anime Crossover Defense

A screenshot showing the Artifact Rift setup process in Anime Crossover Defense.
Head to the Artifact Rift an insert Rift Orbs or Legendary Rift Orbs to earn the chance to obtain Artifacts in Anime Crossover Defense.

Artifacts are sometimes obtained by completing Artifact Rifts. You can access these through the Artifact Rift gate in the top-right corner of the lobby.

Artifact Rifts require Rift Orbs or Legendary Rift Orbs to challenge – with up to three of any kind useable at once.

The more Orbs you use, and the rarer they are, the higher chance you’ll have of gaining an Artifact if you complete the rift.

Once obtained, you can see and equip your artifacts in the Artifacts tab of the inventory screen.


Still learning the ropes? Study the Anime Crossover Defense Trello. And for high-ranking units, use the latest Anime Crossover Defense codes and use the rewards to pull for the best units on the ACD tier list..

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